Discordant twins as a tool to unravel the aetiology of bipolar disorder
9 Citations•2014•
C. Fagnani, M. Bellani, J. Soares
Epidemiology and Psychiatric Sciences
This editorial focuses on discordant twins as a valuable epidemiological design for psychiatric aetiological research, and draws attention to the use of this method in bipolar disorder, revising previous discordant-twin studies.
Abstract
This editorial focuses on discordant twins as a valuable epidemiological design for psychiatric aetiological research. First, we summarise the advantages and strengths of this design over the classical matched case-control study. Then, we draw attention to the use of this method in bipolar disorder, revising previous discordant-twin studies. A future greater use of discordant twins is desirable to gain further relevant insights in the aetiology of bipolar disorder.