Confusion about New Zealand abortion.
It seems clear that the immunological equilibrium existing throughout pregnancy is a dynamic multifactorial system with a steady interchange of immune information and a concominant ever-changing series of reactions.
Abstract
the embryonic circulatory system has developed interchange of transplantation antigens is possible; before this some traffic of trophoblastic cells or of subcellular material from the fetal complex to the mother may occur, while the passage of immunopotent substances into the embryo from the maternal circulation is also a possibility. Antigen thus transferred could be not only non-sensitising in form and amount but also capable of defunctioning rejection mechanisms in ways previously reviewed' and artificially explored.6 Whichever of these hypothetical mechanisms may be shared with the cancer-host and the surgical transplant-recipient systems, it seems clear that the immunological equilibrium existing throughout pregnancy is a dynamic multifactorial system with a steady interchange of immune information and a concominant ever-changing series of reactions. Knowledge of the kinetics of humoral and cellular responses to the two-way traffic in transplantation antigens is the central need of further understanding.