This study aimed to investigate the association between the Generalized Anxiety Disorder 2‐item scale polygenic score with anxiety in MS.
Comorbid anxiety occurs often in MS and is associated with disability progression. Polygenic scores offer a possible means of anxiety risk prediction but often have not been validated outside the original discovery population. We aimed to investigate the association between the Generalized Anxiety Disorder 2‐item scale polygenic score with anxiety in MS.