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Chemoradiation therapy changes oral microbiome and metabolomic profiles in patients with oral cavity cancer and oropharyngeal cancer

DOI: 10.1002/hed.26619Semantic Scholar
15 Citations•2021•
Yenkai Lim, K. Tang, A. Karpe
Head & Neck

Patients with oral cavity cancer (OCC) and oropharyngeal cancer (OPC) are often seen with locoregionally advanced disease requiring complex multimodality treatments, which may have detrimental effects on the oral microbiome.

Abstract

Patients with oral cavity cancer (OCC) and oropharyngeal cancer (OPC) are often seen with locoregionally advanced disease requiring complex multimodality treatments. These treatments may have detrimental effects on the oral microbiome, which is critical to maintaining physiological balance and health.