Ulcerative Colitis
The muscle hypertrophy and the perforation would conform with Wilson's theory of appendiceal diverticula,l which in the absence of a constriction must represent the continuous efforts of the appendix to expel its unusually profuse and viscous secretions.
Abstract
I am grateful to Dr. Whitelaw for the following histological report. " Ovarian tissue shows a follicular cyst filled with blood clot. Section of appendix is cyst-like in character with diameter of lumen 1.0 cm. In the specimen there is no occluding stricture. The wall is composed of a lining of high mucus-secreting columnar cells. There are no remains of cysts, and lumen is filled with mucin material with a few scattered cells. The submucosa is narrowed, fibrous, and has a few scattered lymphoid follicles. The muscular coat is of considerable thickness (1.7 mm.) and in two places is ruptured or deficient, and the mucous contents pour through and infiltrate the peritoneal coat. The cells associated with the 'mucin' are plasma cells and round cells and a few foreign body giant cells. There are no cells of epithelial origin in this over-spill." The patient had an uneventful convalescence, and subsequent questioning failed to elicit any history that could have been construed as appendicitis. The muscle hypertrophy and the perforation would conform with Wilson's theory of appendiceal diverticula,l which in the absence of a constriction must represent the continuous efforts of the appendix to expel its unusually profuse and viscous secretions.