Iraarticular injection of endostatin can be useful to RA patients and 68% of patients acquired clinical remission at last.
Objective To investigate the effects of endostatin on patients of rheumatoid arthritis(RA) by intraarticular injection.Method 18 patients of RA were recruited from our hospital.Besides the use of methotrexate,Salicylazosulfapyridin and other academic therapies,all of them received endostatin 750ug every week by intraarticular injection with a total of 6 times.And 17 patients received normal management without intraarticular injection were compared Result 68% of patients acquired clinical remission at last.Conclusion Intraarticular injection of endostatin can be useful to RA patients