[Modern achievements in genetic studies of idiopathic generalized epilepsies].
2 Citations•2018•
Z. Afawi, R. G. Gamirova, A. Jaxybayeva
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Already identified genes are described, which are a causative factor of idiopathic generalized epilepsies, and further prospects of using molecular genetic studies are discussed.
Abstract
The review presents modern data on the genetics of idiopathic generalized epilepsies. Identified genes encode different structures of neurons, including voltage-dependent channels, receptors of neurotransmitters, protein-associated ion channels and synaptic proteins. The authors describe already identified genes, which are a causative factor of idiopathic generalized epilepsies and discuss further prospects of using molecular genetic studies.