This study reviewed recent findings about the role of ER stress and OS in the pathogenesis of inflammatory diseases and suggested that acute or chronic inflammation is a major cause of disease.
Endoplasmic reticulum (ER) stress and oxidative stress (OS) are often related states in cells as part of normal physiology but more frequently manifested in the pathophysiology of many diseases, particularly diseases involving acute or chronic inflammation. In this study, we reviewed recent findings about the role of ER stress and OS in the pathogenesis of inflammatory diseases.