PP.29.22: FACTORS ASSOCIATED WITH HIGH BLOOD PRESSURE, ELEVATED BLOOD PRESSURE, ISOLATED SYSTOLIC HYPERTENSION AND HYPERTENSION IN ELDERLY RUSSIANS
Lower educational levels are associated with HBP, EBP and AH only in men, and smoking and hypercholesterolemia fails to demonstrate a clear association with AH, ISH, and HBP or EBP in both genders.
Abstract
Objective: to assess factors associated with high blood pressure (HBP), elevated BP (EBP), isolated systolic hypertension (ISH) and arterial hypertension (AH) in representative Moscow sample. Design and method: A prospective study SAHR (Stress, Aging and Health in Russia) was carried out in a population-based sample of Muscovites aged > 55 years (N -1800, response rate > 80%). Education, smoking, alcohol consumption, major cardiovascular (CV) events, BP, heart rate, body mass index, fasting total cholesterol, glycated haemoglobin (HbA1c), left ventricular hypertrophy (LVH) were assessed. HBP was defined as SBP > 160 mmHg and/or DBP > 95 mm Hg; EBP - SBP > 140 mmHg and/or DBP > 90 mmHg and ISH - SBP > 140 mmHg and DBP < 90 mmHg. AH - EBP or use of antihypertensive drugs. Results: Obesity and elevated HbA1c in women are significantly associated with AH (OR: 2.45, 95%CI 1.79; 3.36; OR: 3.84, 95%CI 2.11; 6.99), with HBP and EBP. Both HBP and EBP are significantly linked to LVH (HBP - OR: 2.90, 95%CI 1.71; 4.91); lower education is associated only with HBP (OR: 2.13, 95%CI 1.55; 2.92). In men, the factors linked to EBP, HBP, and AH include obesity (AH - OR: 4.19, 95%CI 2.62; 6.69) and LVH (HBP – OR: 3.07, 95%CI 1.83; 5.16), but not elevated HbA1c. Lower-educated men have significantly higher odds of high (OR: 2.09, 95%CI 1.55, 2.82) and EBP. High alcohol consumption is associated with EBP (OR: 2.10, 95%CI 1.23, 3.56) and ISH (OR: 1.74, 95%CI 1.04, 2.93), while heart rate > 80 bpm is linked to HBP (OR: 1.60, 95%CI 1.15, 2.24), and CV events are related to AH (OR: 1.85, 95%CI 1.18, 2.90). Smoking and hypercholesterolemia fails to demonstrate a clear association with AH, ISH, and HBP or EBP in both genders. Conclusions: Lower educational levels are associated with HBP, EBP and AH only in men. AH is more common in obese persons. The adjusted association between hypertension and elevated HbA1c is significant only in women. LVH is significantly linked to HBP and EBP or AH in men, and to HBP or EBP in SAHR women.