Genetics of bipolar disorder
83 Citations•2020•
F. McMahon, S. Detera-Wadleigh
New Oxford Textbook of Psychiatry
This chapter reviews the genetic epidemiology, molecular genetics, and genetic modelling studies of bipolar disorder and anticipates some future research directions of relevance to clinical care.
Abstract
Bipolar disorder represents one of the most highly heritable group of common psychiatric disorders, but the complex genetic basis of these disorders has only recently begun to reveal itself. This chapter reviews the genetic epidemiology, molecular genetics, and genetic modelling studies of bipolar disorder. The chapter concludes with a glimpse of anticipated developments of relevance to clinical care and anticipates some future research directions.