Radiotherapy and immunology
28 Citations•2024•
Liangliang Wang, C. Lynch, S. Pitroda
The Journal of Experimental Medicine
Preclinical and clinical data related to the importance of immune responses to radiotherapy-induced anti-tumor effects, as well as blockade of immune checkpoints PD-1/PD-L1 and/or CTLA-4 in combination with radiotherapy are reviewed.
Abstract
The majority of cancer patients receive radiotherapy. Wang et al. review preclinical and clinical data related to the importance of immune responses to radiotherapy-induced anti-tumor effects, as well as blockade of immune checkpoints PD-1/PD-L1 and/or CTLA-4 in combination with radiotherapy.