Synthesis and characterization of some new heterocyclic compounds
This work includes preparing of some new derivatives of pyrimidine,pyrazolidine, and isoxazolidine from the reaction between tetraethyl and ammonia derivatives in dry ethanol to obtain six membered hetero rings.
Abstract
This work includes preparing of some new derivatives of pyrimidine ,pyrazolidine, and isoxazolidine from the reaction between tetraethyl 2,2' -(1E,1E' )- biphenyl ll-4, 4' -diylbis(diazene-1,2-diyl)dimalonate(1) and ammonia derivatives in dry ethanol to obtain the six membered hetero rings: 5,5'-(1E,1E') biphenyl-4,4'-diylbis (diazo-1,2-diyl)bis(2-mercaptopyrimidine-4,6-diol)(2) ; 5,5'-(1E,1E' ) biphenyl-4,4'-diylbis(diazo-1,2-diyl)dipyrimidine-2,4,6-triol(3);5,5'-(1E,1E')-biphenyl-4,4'-diylbis (diazo-1,2-diyl)bis(2-aminopyridine-4,6-diol)(4); and five membered hetero ring: 4,4' -(1E,1E')-biphenyl-4,4'-diylbis(diazene-1,2-diyl)dipyrazolidine-3,5-dione(5);4,4'-(1E , 1E')-biphenyl-4,4'-diylbis(diazene-1,2-diyl)bis(1-phenylpyrazolidine-3,5-dione)(6); 4,4'-(1E,1E')-biphenyl-4,4'-diylbis (diazene-1,2-diyl)diisoxazolidine-3,5-dione)(7). The prepared compounds were characterized by spectral methods FT-IR ,1H-NMR and measurement of some of its physical properties ; and the reaction was followed by TLC.