Of the brain, by the brain, and for the brain

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Abstract

Circa 400 bc, Hippocrates made the first postulate regarding the origin of all human emotion and declared, “Men ought to know that from the brain, and from the brain only, arise our pleasures, joy, laughter and jests, as well as our sorrows, pains, griefs, and tears.”1 How does a barrage of action potentials, cascading down a neuron, accomplish these extraordinary feats? How do we explain love at first saccade? And how does the brain contemplate the vastness of this universe? Such beguiling complexities keep “us” at the study of the neurosciences.