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DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with ulcerative colitis (UC)

31 Citations2010
R. Arasaradnam, K. Khoo, M. Bradburn
Epigenetics

Few studies exist on alteration in DNA methylation profiles (genomic and gene specific methylation) in patients with Ulcerative Colitis and none assessing its relationship with lifestyle exposures.

Abstract

Epigenetic marking such as DNA methylation influence gene transcription and chromosomal stability and may also be affected by environmental exposures. Few studies exist on alteration in DNA methylation profiles (genomic and gene specific methylation) in patients with Ulcerative Colitis (UC) and none assessing its relationship with lifestyle exposures.

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