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Bicyclic heterocyclic compound

2 Citations2008
요시후미 가가미이시, 테츠지 사이토, 테츠오 오비츠
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The compound is useful as a medicinal ingredient having a CRF antagonistic activity for use in the prevention and/or treatment of a neurological/psychiatric disease, a disease in a terminal organ or the like.

Abstract

Disclosed is a medicinal agent comprising, as an active ingredient, a compound having a CRF antagonistic activity for use in the prevention and/or treatment of a neurological/psychiatric disease, a disease in a terminal organ or the like. Specifically disclosed is a compound represented by the general formula (I), a salt, N-oxide or solvate thereof, or a prodrug of the compound, the salt, the N-oxide or the solvate. The compound is useful as a medicinal ingredient having a CRF antagonistic activity for use in the prevention and/or treatment of a neurological/psychiatric disease, a disease in a terminal organ or the like. (I) wherein Rrepresents a branched Calkyl group which may be substituted or the like; Rrepresents a hydrogen atom or a Calkyl group which may be substituted; Rrepresents a Calkyl group which may be substituted or a halogen atom; Rrepresents a Calkyl group which may be substituted or the like; and ''ring1'' represents a cyclic group having planarity which may be substituted.

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