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Investigating raised creatine kinase

4 Citations•2021•
Eun Ji Kim, A. Wierzbicki
BMJ

Measure creatine kinase if a patient on statin therapy develops muscle pain and warrant investigation for underlying secondary causes including endocrine, autoimmune, and genetic disorders.

Abstract

• What you need to know • Most elevations in creatine kinase are physiological or secondary to exercise and do not require further investigation unless likely to be secondary to newly prescribed drug therapies • Persistent symptomatic changes in creatine kinase warrant investigation for underlying secondary causes including endocrine, autoimmune, and genetic disorders • Measure creatine kinase if a patient on statin therapy develops muscle pain