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Immune to weight loss

88 Citations•2006•
W. Wells
The Journal of Cell Biology

It is shown that leptin prevents CRP from reducing body weight, and this results implies that leptin-like signals in the gut may be responsible for weight loss in chronically undernourished people.

Abstract

![][1] CRP prevents leptin from reducing body weight. ZHAO/MACMILLAN Leptin always seemed a bit too good to be true. Why would our chronically undernourished ancestors have evolved a hormone for weight loss? Now, Ke Chen, Allan Zhao (University of Pittsburgh, PA), and colleagues