Medicinal agent for treatment of hypertension or high blood pressure
The proposed agent contains synergism of lower blood pressure on a model of spontaneous hypertension and its salts applicable from the point of view of medicine.
Abstract
FIELD: pharmacology. SUBSTANCE: invention relates to a therapeutical or preventive agent for treatment of hypertension or high blood pressure and to the appropriate method of treatment with its usage. The proposed agent contains (a) and (b) as active ingredients: (a) 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolcarbonic acid (febuxostat) or its pharmaceutically acceptable salt; (b) a compound selected from a group made of blockers of calcium channels, blockers of a receptor of angiotensin II, and inhibitors of an angiotensin-converting ferment and their salts applicable from the point of view of medicine. EFFECT: synergism of lower blood pressure on a model of spontaneous hypertension. 9 cl, 4 tbl