Systems biology as a field continues to grow with PubMed listing 21,352 papers published as of mid December of 2014, and the inherent unpredictable nature of complex systems has led to many failures in research in general and in translational research in particular.
Systems biology as a field continues to grow with PubMed listing 21,352 papers published as of mid December of 2014. The human body can be described as a system of systems and is classified as a complex system. Not only is the intact human a complex system but it is composed of other systems that are also complex systems. The inherent unpredictable nature of complex systems, along with the corresponding failure of scientists and funding agencies to recognize that humans are complex systems, had led to many failures in research in general and in translational research in particular.