Heterocyclic compounds and their production
No TL;DR found
Abstract
It REFERS TO COMPOUNDS ethenyl-1,3-oxazole-4-METHOXY of formula I, wherein n is 1-2; R1 is halogenated C1-C2 optionally halogen; One of R2 and R3 is H, the other is a group a, b; n is 3-4; R4 is C1-C4 substituted with OH. Preferred compounds 1-4- {4 - [(2 - {(E) -2- [4- (trifluoromethyl) phenyl] ethenyl} -1,3-oxazol-4-yl) methoxy] phenyl} butyl) -1H -1,2,3-triazole; 1- (3- {3 - [(2 - {(E) -2- [4- (trifluoromethyl) phenyl] ethenyl} -1,3-oxazole-4-yl) methoxy] phenyl) propyl) -1H-1 , 2,3-triazole; 3-1- {4- [4 - ({2 - [(E) -2- (2,4-difluorophenyl) ethenyl] -1,3-oxazole-4-yl} methoxy) phenyl] butyl) -1H- imidazol-2-yl) -1,2-propanediol. Also it relates to a method for the preparation; A specific compound of formula II; A A composition comprising ADDITION OTHER THERAPEUTIC AGENTS ANTICANCER AGENTS OR HORMONE (modulator OF LHRH AS leuprorelin). The compound is an inhibitor of tyrosine kinase and may be useful to prevent or treat breast cancer, prostate