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Part 1 Underlying principles: the relationship between mental retardation, autism and autistic-like conditions. Part 2 Research on the population of a clinic for the mentally retarded: general profile of the entire group of children admitted to the observation home comparison of the children in the study with and without a pervasive developmental disorder problems with classification and diagnosis in everyday clinical practice aspects of management and treatment of mentally retarded children with a PDD how do mentally retarded children with a PDD fare after discharge from the observation home? Part 3 Diagnostics, prevalence and special problems: diagnosis of pervasive developmental disorders in mentally retarded people prevalence of pervasive developmental disorders in mentally retarded people pervasive developmental disorders and temperament self-enclosed behaviour in pervasive developmental disorders pervasive developmental disorders in persons with Down Syndrome pervasive developmental disorders in males with Fragile-X Syndrome.