Association of hypothyroidism and polycystic ovary syndrome (PCOS)
There is increased prevalence of hypothyroidism in patients with PCOS, more common in the age group of 26-30 years, and Screening for hypothy thyroid profile in PCOS patients will decrease the morbidity, improving quality of life.
Abstract
Introduction: Polycystic ovarian syndrome (PCOS) and hypothyroidism are the most common endocrine disorders in women of reproductive age group and both these disorders present with complaints of menstrual irregularities like oligomenorrhoea, secondary amenorrhoea and sometimes menorrhagia. The relationship between hypothyroidism and PCOS is not clearly understood. Aim and Objective: To determine the association between thyroid profile and polycystic ovary syndrome (PCOS) Materials and Methods: This is a retrospective study on 71 patients with PCOS at Sri Ramachandra medical centre, over a period of 6 months. In this study, PCOS was diagnosed based on Rotterdam criteria and patient details regarding history, physical examination and thyroid profile were obtained. In all these patients, thyroid profile was analysed in Beckman coulter DXI 800 based on the principle CLIA. Results: Statistical analysis was done using SPSS software version 13.0. Student t test was performed and p value < 0.05 considered to be significant. The p value is not statistically correlated for TSH and age to hypothyroidism and other presenting complaints. Discussion: PCOS was more common in the age group of 26-30 years. 18% of PCOS patients diagnosed to have hypothyroidism, 4% patients found to have Sub-clinical hypothyroidism and rest 78% were euthyroid. 46% of PCOS patients presented with complaints of irregular menstrual cycle, 31% with complaints of infertility and 23% with other complaints. Conclusion: There is increased prevalence of hypothyroidism in patients with PCOS. Similarly, the coexistence of hypothyroidism and PCOS can lead to severity of complaints in hypothyroid patients. Screening for hypothyroidism in PCOS patients will decrease the morbidity. Thus improving quality of life. © 2019 Published by Innovative Publication.