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Home / Papers / Goshajinkigan increases peripheral capillary diameter in non‐diabetic and diabetic mice

Goshajinkigan increases peripheral capillary diameter in non‐diabetic and diabetic mice

DOI: 10.1002/tkm2.1267Semantic Scholar
1 Citations•2020•
Koki Inagaki, M. Furuta, Izumi Asada
Traditional & Kampo Medicine

The involvement of NO in the vasodilatory effect of GJG in peripheral capillaries is investigated to clarify the mechanism related to DPN symptom improvement.

Abstract

Goshajinkigan (GJG) improves hyperesthesia and hypoesthesia in diabetic peripheral neuropathy (DPN) by increasing nitric oxide (NO) production. In this study, we investigated the involvement of NO in the vasodilatory effect of GJG in peripheral capillaries to clarify the mechanism related to DPN symptom improvement.