nNOS at a glance: implications for brain and brawn
102 Citations•2004•
Imran N. Mungrue, D. Bredt
Journal of Cell Science
The first NO synthase (NOS) was isolated from mammalian brain and named neuronal NOS (nNOS, aka: NOS1) owing to its similarity to NOS2.
Abstract
Nitric oxide (NO), formed enzymatically from L-arginine, functions as an endogenous signaling molecule in numerous organs and tissues throughout the animal and plant kingdoms. The first NO synthase (NOS) was isolated from mammalian brain and named neuronal NOS (nNOS, aka: NOS1) owing to its