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Audiogenic kindling in Wistar and WAG/Rij rats: Kindling‐prone and kindling‐resistant subpopulations
22 Citations•2008•
L. Vinogradova
Epilepsia
Audiogenic kindling is a model of naturally occurring epileptogenesis triggered by repeated sound stimulation of rats genetically prone to audiogenic seizures and progression in rats susceptible and unsusceptible to absence seizures is investigated.
Abstract
Purpose: Audiogenic kindling (AK) is a model of naturally occurring epileptogenesis triggered by repeated sound stimulation of rats genetically prone to audiogenic seizures. It is accepted that limbic seizure networks underlie progressive changes in behavioral seizure pattern during AK. The present study investigated AK progression in rats susceptible and unsusceptible to absence seizures.