Top Research Papers on Oral Cancer

The oral cavity is a key anatomic location and yet in the course of professional training of physicians, dentists, and other health professionals, it is often given only modest attention.

A 53-year-old male who had smoked for 36 years was referred by his dentist for worsening vitiligo diagnosed as leukoplakia 3 years earlier.

To improve survival, all patients should be routinely and vigilantly screened for oral mucosal lesions, particularly the increasing incidence in young patients without traditional risk factors of alcohol and tobacco abuse.

Anatomical factors which play a major role in the clinical behaviour of cancers of the tongue, floor of mouth and lower alveolus, dentate and edentulous, are described and the influence of anatomical factors in the surgical approach to these tumors is discussed.

The importance of education of both physicians and patients in achieving the goal of earlier diagnosis of oral cancer is stressed and warning signs of cancerous oral lesions, diagnosis, and treatment choices are discussed.

There were 299,051 cases of lip and oral cavity cancers in 2012 and 145,353 deaths worldwide: adding those with oro-and hypo-pharynx cancers, raising this figure to 441,000 cases per year and 241,458 deaths.

This paper reviews the Japanese literature regarding sentinel lymph node localization in head and neck surgery and relevant domestic and foreign articles from other fields of medicine, and reports our results. Even though we have less experience with it in Japan, we believe the sentinel node concept for the head and neck region will be established. Further investigation and practical application in clinical settings are anticipated in the future.

An overview of cancer, oral cavity, diagnosis, complications, medical treatments and self-prevention to avoid risk factors is provided.

The epidemiology and risk factors for oral cancer in Australia, the various clinical presentations that occur and the staging of oral cancer are highlighted.

Oral cancers are found on the tongue, the bottom or roof of the mouth, in the tonsils, on the salivary glands, and in the back of the throat.

The survival of patients with oral cancer remains poor despite recent surgical advances. About 30-40% of patients with intra-oral cancers will survive five years; the short survival time is caused, largely, by late detection. Public awareness of oral cancer as compared with other cancers is low and this contributes to delays in diagnosis. However, the mouth can be examined by healthcare professionals with much greater ease and accuracy than many other parts of the body. All healthcare workers need to be aware that a patient with an ulcer or white patch that persists beyond three weeks should b...

The results suggest that some students are fully aware of oral cancer and some have little knowledge about this disease.

In the U.S. oral cancer accounts for 2.1% of all cancers and 1% of cancer deaths, and two to three times as many males as females are affected.

Vital staining with toluidine blue and exfoliative cytological examination can aid early detection by accelerating the biopsy of lesions that cannot be classified adequately or made to disappear.

Cancers of the oral cavity and surrounding structures constitute approximately 3% of malignancies in the Lancaster area, the majority of which are squamous cell carcinomas, which can be very distressing to patients and relatives alike.

Oral cancer is relatively uncommon in the UK, accounting for 2% of all cancers, in India and parts of South-East Asia it is the most common malignant neoplasm and accounts for around a third of all illnesses, and data suggest that oral cancer is uncommon, but there are enormous variations worldwide.

Oral cancer shows three clinical aspects: exophytic, ulcerative and infiltrative; lips and margins of tongue are the most interested sites; for the diagnosis a correct clinical examination and a biopsy, possibly made with incisional criteria are necessary.

Although the evidence to support routine annual screening for oral cancers is inconclusive, family physicians and dental practitioners should be attentive to precursor lesions, such as leukoplakia and erythroplakia, and strongly consider obtaining or referring for biopsy patients with suspicious lesions.

An overview of cancer (and in particular oral cancer) is presented as well as statistical information on cancer incidence and mortality, etiology, treatment modalities, head and neck cancers, their signs and symptoms, prognosis, and pre-treatment dental evaluations are presented.

TLC count, neutrophil count and lymphocyte count might prove as useful determinant factor in oral squamous cell carcinoma and oral potentially malignant disorders, however, further study is required to establish their role as diagnostic, prognostic marker or predictor of malignant transformation.

The study of the geographic distribution of oral cancer shows some interesting geographic features, the study of which is providing data useful for planning practical preventive measures.

The in vitro growth of living cells in a suitable microenvironment constitutes cell culture and the progression of cell-to tissue-to organ-level culturing in vitro is the most impressive.

The importance of bacteria level and composition in the transition of oral precancerous lesions to cancer has been demonstrated and the relationship of changes in microbiome composition with smoking, inflammation in healthy individuals, as well as with the development of oral cancer in patients has been studied.

Screening test for OSCC based on determination of salivary NO levels could be appealing and may prove to be useful assay for diagnosis and early detection of disease progression in oral cancer.

A need for interventions designed to increase knowledge levels of risk factors for, signs, and symptoms of oral cancers and the need for oral cancer examinations is demonstrated.

It was found that the majority of users who post on Twitter were individuals, and the most common tweets were posted from the USA.

Oral cancer American cancer society , Oral cancer American cancer society , کتابخانه دیجیتال جندی شاپور اهواز

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The role of the oral microbiome, focusing on its bacterial fraction, in cancer in general and in OSCC more precisely, is summarized and a brief description of the potential use of bacteria to target tumors is described.

This review aimed to present the fundamental aspects of tumor immunity and immunotherapy, focused on oral squamous cell carcinoma.

The human microbiome is defined as the collective genomes of the microbes that live inside and on the human body, and there are approximately 10 microbes and 100 microbial genes for each human cell and gene respectively.

Oral squamous cell carcinoma is described as an invasive epithelial neoplasm with varying degrees of squamous differentiation and a propensity to early and extensive lymph node metastases, occurring predominantly in alcohol and tobacco using adults generally in the 5th and 6th decades of life.

A 76-year-old man with chronic obstructive lung disease and a 60 pack-year history of smoking presented with diffuse lesions on his tongue that had been evolving for three years and all lesions were surgically removed.

Exposure to the human papilloma virus through oral sex has become the fastest growing risk factor for oral cancer – affecting unprecedented numbers of otherwise healthy young people in their twenties and thirties.

Oral and oro‐pharyngeal cancer is a global health problem, with over 500’000 new cases diagnosed per annum worldwide and in parts of in the Indian subcontinent oral cancer constitutes up to 40% of all cancers.

The herpes simplex virus type 1 has been associated with oral cancer by serological studies, and animal models and in vitro systems have demonstrated that it is capable of inducing oral cancer.

Results of an analysis of data from 1460 unselected patients admitted to the Tata Memorial Hospital during 1952-1954 yielded the following findings: the habit of chewing tobacco was associated with cancer of the oral cavity and the combined habits of smoking and chewing withcancer of the hypopharynx and base of the tongue.

The central theme of this paper will be the evaluation of still another entity that for many years has been suspected as an important link in the chain of factors influencing neoplastic transformation in oral and other tissues, which is in widespread use by humans around the world.

The article reviews some of the results of studies on the effects of OC use on ovarian, uterine, cervical, and breast cancer and on hepatic cancer and melanomas and concludes that OCs protect against ovarian and uterine cancers and do not cause mammary, cervical- or liver cancer or melanoma.

The findings and other reports of an increased risk among persons ordinarily at low risk of this disease raise the possibility that mouthwash may contribute to oral and pharyngeal cancers.

This regimen has almost completely eliminated cases of symptomatic osteoradionecrosis requiring resection or reconstruction with or without hyperbaric oxygen.

The combined therapy with superselective intra-arterial chemoradiotherapy and RF hyperthermia was effective therapy for advanced oral cancer with cervical lymph node metastasis (N3), and this therapy is promising as a new strategy of non-invasive therapy forAdvanced oral cancer.

This review highlights the efficacy of various diagnostic methods in screening of oral cancer including toluidine blue staining, brush biopsy, chemiluminescence and tissue autofluorescence.

Ankylosing Spondylitis and Spinal Osteotomy From Mr W. Alexander Law The London Hospital, Whitechapel, London Dear Sir, Thank you for letting me see a copy of Dr Dixon's letter concerning my paper in the October issue.

Evidence in support of a chemopreven- tive role for the so-called antioxidant nutrients, /3-carotene and vitamin E, against oral cavity cancer is presented from lab- oratory studies, animal model systems, and cancer incidence reduction trials in high-risk groups.

Oral cancer, predominantly oral squamous cell carcinoma (OSCC), is a significant health problem and is regarded as the main cause of death from oral diseases in many countries.

In two instances a definite elevation of the values of serum amylase and lipase was demonstrated, suggestive of an associated pancreatic disturbance in patients with infectious mononueleosis.

There is no evidence that the Pill increases the risk of breast cancer and in fact, it has been shown that oral contraceptives may offer some protection against benign breast disease.

The relationship between mitophagy, tumorogenesis, and cell death plays an important role in the identification of potential targets of cell death and selective wiping out of cancer cells.

There is growing incidence of oral cancer in India, persisting poor awareness about the need to quit tobacco/areca nut/alcohol use and go for screening, and major efforts are needed to implement preventive activities.