Top Research Papers on Stress

An elastoviscoplastic constitutive equation is proposed to describe both the elastic and rate-dependent plastic deformation behavior of Carbopol® dispersions, commonly used to study yield-stress fluids. The model, a variant of the nonlinear Maxwell model with stress-dependent relaxation time, eliminates the need for a separate Herschel–Bulkley yield stress. The stress dependence of the viscosity was determined experimentally by evaluating the steady-state flow stress at a constant applied shear rate and by measuring the steady-state creep rate at constant applied shear stress. Experimentally, ...

This review assesses how UPR signaling mediators can influence antioxidant responses and how oxidative stress can disrupt the function of redox-sensitive organelles including the mitochondria and endoplasmic reticulum.

It is found although the concept of stress is developed from Selye's “general adaptation syndrome”, it has now expanded and evolved significantly and is now defined as a state of homeostasis being challenged, including both system stress and local stress.

The purpose of the review is to critically evaluate the effects of various stress stimuli on higher plants with an emphasis on the typical and distinctive dose-dependent responses that are essential for plant growth and development.

This review focuses on the link between oxidative stress and the stress response, neuroinflammation, serotonergic pathways, neurogenesis, and synaptic plasticity’s imbalances present in depression.

Changes in parent stress longitudinally from before (retrospective) to two timepoints during COVID-19 are described, suggesting the need for enhanced mental health resources and supports.

The current knowledge of the general effects of oxidative stress on the central nervous system is reviewed, the different specific routes by which oxidative stress influences the pathophysiologic processes involved in Alzheimer's disease, Parkinson’s disease, Amyotrophic Lateral Sclerosis and Huntington's disease are reviewed, and how oxidative stress may be therapeutically reversed/mitigated in order to stall the pathological progression of these neurodegenerative disorders to bring about clinical benefits are reviewed.

This review is focused on the mechanisms that regulate health, disease and aging redox status, the signal pathways that counteract oxidative and reductive stress, the role of food components and additives with antioxidant properties, and the roles of the hormones irisin and melatonin in the redox homeostasis of animal and human cells.

The physiological, biochemical, and molecular mechanisms underlying abiotics stress-induced anthocyanins in plants and their role in abiotic stress tolerance are discussed and practical guidance for plant biologists who are engineering stress-tolerant crops using Anthocyanin biosynthesis or regulatory genes is provided.

The relationship between misophonia, stress, and traumatic stress has not been well characterized scientifically. This study aimed to explore the relationships among misophonia, stress, lifetime traumatic events, and traumatic stress. A community sample of adults with self-reported misophonia (N = 143) completed structured diagnostic interviews and psychometrically validated self-report measures. Significant positive correlations were observed among perceived stress, traumatic stress, and misophonia severity. However, multivariate analyses revealed that perceived stress significantly predicted...

This review will briefly discuss the adverse effects of key abiotic stresses such as cold, heat, drought, and salinity, and the importance of biotechnological tools in the development of stress-tolerance cultivars.

Metabolic syndrome is a cluster of conditions associated with the risk of diabetes mellitus type 2 and cardiovascular diseases (CVDs). Metabolic syndrome is closely related to obesity. Increased adiposity promotes inflammation and oxidative stress, which are precursors of various complications involving metabolic syndrome components, namely insulin resistance, hypertension, and hyperlipidemia. An increasing number of studies confirm the importance of oxidative stress and chronic inflammation in the etiology of metabolic syndrome. However, few studies have reviewed the mechanisms underlying the...

This review aims at summarizing recent advances in understanding of salt-stress tolerance mechanisms, providing the key background knowledge for improving crops’ salt tolerance, which could contribute to the yield and quality enhancement in major crops grown under saline conditions or in arid and semiarid regions of the world.

The vast majority of agricultural land undergoes abiotic stress that can significantly reduce agricultural yields. Understanding the mechanisms of plant defenses against stresses and putting this knowledge into practice is, therefore, an integral part of sustainable agriculture. In this review, we focus on current findings in plant resistance to four cardinal abiotic stressors—drought, heat, salinity, and low temperatures. Apart from the description of the newly discovered mechanisms of signaling and resistance to abiotic stress, this review also focuses on the importance of primary and second...

The mechanisms and functional significance of communication between the ISR and another key regulator of translation, mTORC1, during acute and chronic amino acid insufficiency are described, to illustrate the synergy between stress pathways.

This work considers possible effects of stress combinations from a theoretical point of view, summarizes the current state of knowledge on signal transduction under single flooding stress, and proposes molecular components of combinatorial flooding (hypoxia) stress adaptation based on their reported dual roles in multiple stresses.

This study reviewed recent findings about the role of ER stress and OS in the pathogenesis of inflammatory diseases and suggested that acute or chronic inflammation is a major cause of disease.

Current knowledge of the contribution of ER stress to the pathogenesis of rheumatic diseases, with a focus on rheumatoid arthritis and systemic lupus erythematosus, is reviewed.

Recent advances in the mechanisms of aging are summarized with an emphasis on mitochondrial dysfunction and ROS production.

Based on experimental evidence, various types of pesticides all seem to have a common effect, the induction of oxidative stress in different cell types and animal models, which is associated with several diseases including cancer, inflammation, and cardiovascular and neurodegenerative diseases.

ABSTRACT This study compared recently divorced Dane’s perceived stress scores with normative data of both (1) general and (2) divorced/separated populations, and investigated the predictive power of sociodemographic- and divorce-related variables on perceived stress. A total of 1,856 divorcees responded to the Perceived Stress Scale and related variables. Recent divorcees had significantly higher perceived stress levels than both the general and the divorced/separated populations. Lower age, lower education level, lower-income, infidelity, former spouse divorce initiation, not having a new par...

The results suggest that the relevance of the information learned to the stressor may play a particularly important role in the effects of stress on memory encoding, which has important implications for theories of stress and memory.

This review presents recent advances in mechanisms of oxidative stress-associated ERS in response to HS, which is destructive to intestinal barrier integrity and the involvement of autophagy and ferroptosis in ERS.

Abstract. The present study analyzed experimentally the association between the experience of psychological stress and the physiological stress response of prospective teachers. The experienced stress was assessed by self-reported data. Cortisol concentrations via saliva samples reflected the physiological response. The results show no difference between the stress and the control group in the experience of psychological stress. However, the stress group had significantly increased cortisol concentrations compared to the control group. The study could not show any correlation between the two s...

This review addresses the role of oxidative stress in the pathogenesis of AGE-related chronic diseases, and recent progress in the development of therapeutics based on antioxidants, AGE breakers and RAGE inhibitors, and outlines therapeutic strategies based on single-atom nanozymes that attenuate oxidative stress through the sequestering of reactive oxygen species (ROS) and reactive nitrogen species ( RNS).

The role of oxidative stress in the pathophysiology of hypertension is reviewed and the potential use of antioxidants in the management of hypertension and its associated organ damage is discussed.

This book discusses Mechanisms of Chilling Injury and Tolerance, Root System Functions During Chilling Temperatures, and Strategies for Coping with Heat Stress.

This chapter describes the adaptations of IPT for treating PTSD, the DSM-5 diagnostic criteria for PTSD, and the research supporting the use of IPT as a non-exposure treatment for this disorder. This research includes a National Institute of Mental Health randomized trial conducted by the author comparing IPT to prolonged exposure therapy and to relaxation therapy, with quite positive results for IPT. Adaptation includes the importance of affective attunement to counter traumatic numbness. There follow three detailed case examples of IPT treatment of complicated grief, role dispute, and role t...

The current evidence supports the possibility that a diet rich in whole plant foods with high antioxidant content along with antioxidant-preserving lifestyle changes may improve bone mineral density and reduce the risk of fragility-related fractures.

The application of SCIPDb is shown in identifying novel candidate genes and pathways for combined drought and pathogen stress tolerance, such as an interactive scrollbar, stress matrix, radial tree, global distribution map, meta-phenome analysis, search, BLAST, transcript expression pattern table, Manhattan plot, and co-expression network.

The current climate change scenario is accelerating degradation, desertification, and salinisation: all destructive processes that are negatively impacting arable lands and food production [...].

These concepts were the basis of the Special Issue that International Journal of Molecular Sciences expressly addressed to the relationship between environmental stresses and plants and that resulted in the publication of 5 reviews and 38 original research articles.

The current study presented the first meta-analytic review on the associations between the Big Five personality traits and stress measured under different conceptualizations (stressor exposure, psychological and physiological stress responses) using a total of 1,575 effect sizes drawn from 298 samples. Overall, neuroticism was found to be positively related to stress, whereas extraversion, agreeableness, conscientiousness, and openness were negatively linked to stress. When stress assessed under different conceptualizations was tested, only neuroticism, agreeableness, and conscientiousness wer...

Aims To explore university students' levels of stress, stressors, and their coping style. Methods A cross-sectional correlational design with a convenience sample (n = 676) of university students who completed the Student-Life Stress Inventory (SSI) and Coping Strategies Indicator (CSI) was used. Findings. Overall, two-thirds of the participant reported moderate levels of stress. Students with chronic illness, living alone, low CGPA, and having exams today experienced a statistically higher mean level of stress. Students who are living alone used the “avoidance” method more significantly and t...

The promise of redox proteomics and systems biology is focused on to help fully understand the relationship between ROS and hypertension and their potential for designing and evaluating novel antihypertensive therapies.

The aim of the present review is to summarize the expanding knowledge on mitokines, the potential to modulate them by lifestyle and their involvement in aging and age‐related diseases, and the importance of well‐balanced mitokine‐levels, the preventive and therapeutic properties of maintainingMitokine homeostasis and sensitivity of mitokin signaling but also the risks arising from the dysregulation ofMitokines.

Analyzing recent literature, a systematic review explores psychological, physiological, and biochemical biomarkers associated with stress and synthesizes findings across these three categories, elucidating their respective roles in stress response mechanisms.

Specimens made of various materials with different geometric features were investigated to predict the failure loads using the recently proposed criterion comprised of both stress and stress gradient conditions. The notch types were cracks and holes, and the materials were brittle, ductile, isotropic, orthotropic, or fibrous composites. The predicted failure stresses or loads were compared to experimental results, and both experimental and theoretically predicted results agreed well for all the different cases. This suggests that the stress and stress-gradient-based failure criterion is both v...

Teachers report elevated levels of stress and psychosomatic illnesses compared to other professions. Teacher stress has far-reaching consequences on their health outcomes, the student's motivation, and the economy. However, research on teacher stress relies mainly on self-reports, hence, assesses stress on purely subjective perception. Personal or subjective aspects can strongly influence these measures, and biological stress may even be unnoticed. It is, therefore, necessary to include both subjective and objective measures to investigate stress, preferably in real-life situations. This revie...

Therapeutic options aimed at disrupting oxidative stress and endoplasmic reticulum stress pathways and their connections including their key intermediary, calcium are highlighted and discussed.

It is revealed that mild stress (2Stress) during the farming period, but without adding excessive alternative protein sources, can improve the stress responsiveness of oscar and it is possible to replace FM with MBM up to 28% without negative effects on the growth and health of juvenile oscar.

There is evidence that stress exposure in childhood and adolescence promotes biological and behavioral alterations that contribute to the multifactorial pathogenesis of obesity.

An overview on the effects of oxidative stress on liver pathophysiology and the mechanisms by which oxidative stress promotes liver disease is provided.

The article addresses recommendations such as complete and proper nutrition, regular physical activity combined with rest, coping skills training, and the most difficult part of all recommendations is their direct fulfilment by children themselves and by their environment, which becomes very important.

The processes of liver injury caused by several types of drugs that induce hepatocyte stress are discussed, focusing primarily on DILI by ERS and mitochondrial stress.

Two decades have passed since Ilan Meyer first published the minority stress theory (MST) model. Since then, scholars have used MST extensively to expand the field's understanding of LGBTQ+ populations' experiences with stress and mental health. To better represent these experiences, scholars have combined MST with other theories in empirical articles, but a theoretical model has yet to be proposed that unifies this work. In the current paper, we seek to acknowledge and extend this work by proposing a Temporal Intersectional Minority Stress (TIMS) model. The TIMS model incorporates Intersectio...

This datasheet on porcine stress syndrome covers Identity, Overview, Distribution, Hosts/Species Affected, Diagnosis, Pathology, Epidemiology, Impacts, Prevention/Control, Further Information.

This paper presents a high-resolution capacitive stress sensor array to precisely characterize the distributed MEMS packaging stress, for the first time. The unit stress measurement cell utilizes a bridge-type mechanical amplifier that converts the substrate strain into capacitance variations. We have measured and compared the MEMS die stress over temperature for different die attaches with a custom designed PCB housing an on-chip heater. The proposed approach significantly simplifies the evaluation and selection of packaging materials. Comparing the temperature responses of a soft silicone-ba...

It is argued that additional emphasis should be placed in future research on investigating sex differences and the impacts of stressor exposure during sensitive periods of development, as well as going beyond traditional morphological measurements to interrogate microglial function.

Introduction Entrepreneurs play a central role in economic and social stability, yet the start-up rate in Germany has declined in recent years, possibly due to the stress associated with entrepreneurial endeavors. Stressors such as financial uncertainty and time pressure are prevalent among entrepreneurs and negatively affect their psychological well-being. However, research on stress management strategies among self-employed individuals remains limited. Methods This pilot study conducted a quantitative analysis with 117 self-employed participants in Germany. The study focused on typical entre...