Top Research Papers on Stress

It is found although the concept of stress is developed from Selye's “general adaptation syndrome”, it has now expanded and evolved significantly and is now defined as a state of homeostasis being challenged, including both system stress and local stress.

Grand challenges in understanding stress-induced RNA condensation are outlined, centering on the unique and substantial barriers in the molecular study of cellular structures, such as stress granules, for which no biological function has been firmly established.

This review will briefly discuss the adverse effects of key abiotic stresses such as cold, heat, drought, and salinity, and the importance of biotechnological tools in the development of stress-tolerance cultivars.

It is explained how altering second-level valuation systems-shifting the valuation of stress from "is bad for me" to "can be good for me"-fundamentally changes the overarching goal of stress regulation from reducing stress to optimizing stress responses to achieve valued goals.

Part One: Theoretical Perspectives in Occupational Research Psychological Stress in the Workplace Work Stress Conceived and Researched Transactionally Measuring Occupational Stress: The Job Stress Survey. Part Two: Sources and Consequences of Occupational Stress: Model Testing Coping with Stressful Life Events: An Empirical Analysis A Field Study of Some Antecedents and Consequences of Felt Job Stress. Part Three: The Impact of Persistence on Stressor-Strain and Strain-Intentions to Leave Relationships: A Field Examination. Part Four: An Examination of Burnout Individual, Organisational, and S...

How and to what extent Pro is involved in relieving oxidative stress to regulate plant survival under extreme environments is discussed and an overview on adopting advanced genome-editing technologies, such as CRISPR, for editing appropriate genes of Pro metabolism aiming to develop stress-resistant crop plants is presented.

This review assesses how UPR signaling mediators can influence antioxidant responses and how oxidative stress can disrupt the function of redox-sensitive organelles including the mitochondria and endoplasmic reticulum.

A conceptual model of acute and chronic stress pathophysiology as a continuum in chronic disease development is discussed and a brief overview on the organization and physiology of the human stress system and its (re)activity is offered.

Changes in parent stress longitudinally from before (retrospective) to two timepoints during COVID-19 are described, suggesting the need for enhanced mental health resources and supports.

Comparison of tolerant and susceptible potato cultivars indicates that single and multiple abiotic stress tolerance in potato is associated with a maintenance of CO2 assimilation and protection of PSII by a reduction of light harvesting capacity and suggests that stress tolerant cultivars suppress cell death and maintain growth and development via fine tuning of hormone signaling, and primary and secondary metabolism.

Recent studies suggesting that reciprocal regulation between stress-response and growth-control pathways occurs at multiple levels will be critical for resetting the balance between stress resistance and growth in order to engineer stress-resistant and high-yielding crops.

This review outlines the contributions of autophagy, oxidative stress, and ER stress in neurodegenerative conditions along with a particular focus on the crosstalk among these pathways and provides a comprehensive discussion on the potential of nanomaterials to target this crosStalk and suggest this potential as a promising opportunity in neuroprotection.

The physiological, biochemical, and molecular mechanisms underlying abiotics stress-induced anthocyanins in plants and their role in abiotic stress tolerance are discussed and practical guidance for plant biologists who are engineering stress-tolerant crops using Anthocyanin biosynthesis or regulatory genes is provided.

A BDNF stress–sensitivity hypothesis is proposed, which posits that disruption of endogenous BDNF activity by common factors potentiates sensitivity to stress and, by extension, vulnerability to stress-inducible illnesses.

The mechanisms underlying susceptibility and resilience to acute and chronic stress are discussed, providing insight into the potential underpinnings of the sex bias of neuropsychiatric disorders.

The current study presented the first meta-analytic review on the associations between the Big Five personality traits and stress measured under different conceptualizations (stressor exposure, psychological and physiological stress responses) using a total of 1,575 effect sizes drawn from 298 samples. Overall, neuroticism was found to be positively related to stress, whereas extraversion, agreeableness, conscientiousness, and openness were negatively linked to stress. When stress assessed under different conceptualizations was tested, only neuroticism, agreeableness, and conscientiousness wer...

Stress incontinence is common among women but underdiagnosed. Effective initial interventions include weight loss in overweight or obese women and pelvic-floor muscle exercises. Other options include pessaries or surgery (most commonly midurethral mesh sling surgery) for women with bothersome symptoms not responsive to other interventions.

The promise of redox proteomics and systems biology is focused on to help fully understand the relationship between ROS and hypertension and their potential for designing and evaluating novel antihypertensive therapies.

The current evidence supports the possibility that a diet rich in whole plant foods with high antioxidant content along with antioxidant-preserving lifestyle changes may improve bone mineral density and reduce the risk of fragility-related fractures.

Plants are continuously exposed to different environmental stress conditions that have a huge impact on agriculture worldwide, consequently leading to massive economic losses. These adverse conditions alter the metabolism of reactive oxygen and nitrogen species (ROS and RNS). High concentrations of these reactive species—that exceed the capacity of antioxidant defense enzymes—disturb redox homeostasis, which can trigger damage to such macromolecules as membrane lipids, proteins, and nucleic acids, ultimately resulting in nitro-oxidative stress and plant cell death. Significant progress has bee...

During progression and metastasis, tumor cells adapt to oxidative stress by increasing NADPH in various ways, including activation of AMPK, the PPP, and reductive glutamine and folate metabolism.

Future studies on the relevance of 4-HNE for the interaction between neuronal cells, notably stem cells and reactive astrocytes might reveal novel options to better monitor and treat consequences or brain injuries, neurodegeneration and regeneration.

A comprehensive strategy that integrates anatomical, biomechanical and biological risk factors has the potential to improve the understanding of bone stress injuries and aid in their prevention and management.

A sound theory of psychological stress must be capable of helping us understand the variations in the ways individuals appraise adaptational transactions with their environments. On the basis of knowledge gained from traditional research methods, there are three main strategies for reducing stress in the workplace. One is to alter the conditions of work so that they are either less stressful or less counterproductive for effective coping. The second strategy is to try to help those who are having difficulty adapting to conditions that are impossible or difficult to change to cope more effectiv...

This article will concern you to try reading stress and mental health as one of the reading material to finish quickly.

It is suggested that transcriptional regulation of stress-responsive genes is an essential step to determine the mechanisms underlying plant stress responses and tolerance to abiotic stress, and that these transcription factors may be important targets for development of crops with enhanced abiotics stress tolerance.

The current article is aimed to summarize the recent updates on H2 S-mediated gene regulation in special reference to abiotic stress tolerance mechanism, and cross adaptation in plants.

This review focuses on the link between oxidative stress and the stress response, neuroinflammation, serotonergic pathways, neurogenesis, and synaptic plasticity’s imbalances present in depression.

The reevaluated concept of the critical role of RBC ROS in the activation of thrombotic events during aging will help identify potential targets for novel strategies to prevent/reduce the risk forVT/E or VT/E recurrences in mid-life stage adults.

Experimental evidence suggests that exogenous antioxidants can reduce or prevent the deleterious effects of pesticides, and limited in vitro studies also suggest that exogenous antioxidants can reduce or prevent the deleterious effects of pesticides.

Measurement invariance analyses demonstrated that varying stress levels of people with a different mental health status are due to true interindividual differences.

This review emphasizes the advancements in various epigenetic-related chromatin modifications, DNA methylation, histone modifications, chromatin remodeling, phytohormones, and microRNAs associated with abiotic stress memory associated with plants.

The metabolic pathways involved in terms of energy homeostasis and ATP production during stress exposure in fish is a new addition here, and has been addressed to some extent in case of temperature and salinity stress.

In vivo research studies on humans about oxidative stress and atopic dermatitis suggest that oxidative stress may have a significant role in atopy dermatitis, but understanding is still incomplete, at least concerning in vivo data, because of limitations of available literature.

The vast majority of agricultural land undergoes abiotic stress that can significantly reduce agricultural yields. Understanding the mechanisms of plant defenses against stresses and putting this knowledge into practice is, therefore, an integral part of sustainable agriculture. In this review, we focus on current findings in plant resistance to four cardinal abiotic stressors—drought, heat, salinity, and low temperatures. Apart from the description of the newly discovered mechanisms of signaling and resistance to abiotic stress, this review also focuses on the importance of primary and second...

Current studies suggest however that state transitions and cyclic electron transport are the main adaptive mechanisms for mediating fluctuating light stress in plants.

Recent advances in the underlying mechanisms that are responsible for stress in promoting malignancies are discussed, providing approaches for NextGen pharmacological therapies, PBI and TCM to reduce the burden of tumorigenesis.

How stress influences dopamine-mediated signaling is reviewed, in particular exploring the hypothesis that the nature of stressful stimuli specifically determines the behavior induced by dopamine and the way signals are perceived in terms of stress or reward.

Host and parasite-derived sources of oxidative stress that may promote severe disease in P. falciparum infection are discussed and therapeutics that restore and maintain oxidative balance in malaria patients may be useful in preventing lethal complications of this disease.

A new integrative framework is provided that links the cellular, systems, and cognitive mechanisms underlying acute stress effects on memory processes and points to potential targets for treating aberrant memory in stress-related mental disorders.