Paperguide

Research-Backed Clinical Trial Design & Protocol Writing

Use AI to research existing trials, analyze study designs, and write protocol sections with proper citations. Build stronger trial protocols more efficiently with comprehensive literature support.

Rated by 1000+ Researchers and Universities

Academics and Professionals from Top Institutions use Paperguide for Research

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Problems We Solve

Literature Research Takes Months

Finding and reviewing relevant trials to support protocol design takes 2-3 months of searching.

Hard to Compare Similar Trials

Manually extracting study designs, endpoints, and methods from dozens of trials is time-consuming.

Writing Protocol Sections is Slow

Creating background sections, study rationale, and methodology descriptions requires extensive literature review and citations.

Missing Important Studies

Manual searches miss relevant trials that could inform better design decisions or safety considerations.

Inconsistent Design Choices

Without comprehensive evidence review, justifying design decisions like endpoints or criteria is difficult.

How Paperguide Works

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Compare Similar Trial Designs

Use Literature Review to extract and compare study designs from multiple trials. See how other studies chose endpoints, inclusion criteria, and statistical methods.

    Find Research Gaps

    Use AI Search to explore current research in your area and see what has been studied. Review the existing evidence to identify gaps and opportunities for your new trial, or use Deep Research to get comprehensive reports that highlight understudied areas.

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      Write Protocol Sections

      Use AI Writer to generate background, rationale, and methodology sections with automatic citations. Get draft content that references relevant studies.

        Why Are We Loving It?

        Know what researchers, students, doctors, and professionals are saying about Paperguide.

        Jacob Johnson

        PhD Researcher

        Helpful for academic researcher. Paperguide is extremely beneficial for academic researchers. It offers numerous features, including a literature table, data extraction, the ability to chat with individual papers, and one-way integration with Zotero reference management software.
        Udomchoke Asawimalkit

        Udomchoke Asawimalkit

        Chiang Mai University

        Paperguide's new 'full document generation' feature stands out as a game-changer, rivaling even the o1 model of ChatGPT. Its ability to intelligently summarize and capture key points, without sacrificing crucial nuances, has saved me hours of laborious analysis. The clean and intuitive interface makes navigating complex literature so easy that I can focus on gleaning insights rather than struggling with clunky software. The personalized recommendations in Paperguide's capability consistently aligne with research outline and suggest valuable resources I wouldn't have found on my own.

        Ronald K

        Management Consultant

        A Productivity Booster for Literature based writing. It impoves finding and managing relevant sources. It increases productivity writing academic and technical articles based on collected and adhoc discoverd sources. It also allows for quick and customizable comparison of sources, within minutes instead of weeks of work.
        David Kocsis

        David Kocsis

        CEO, Wocapi

        EVERYTHING! I can do my research, I can extract data, I can work with PDF file, I can review any literature, I can leave my notes on any file. Like honestly it suits my needs. I run the business across 3 countries, studying my 3x UNI and other additional things so I need to save my time as much as I can and Paperguide does it very well.
        Vugar Ibrahimov

        Vugar Ibrahimov

        Lawyer, PhD Researcher

        When it comes to academic research, time is often a luxury. PaperGuide AI aims to streamline this process, offering tools that answer questions, conduct literature reviews and extract valuable insights from your documents.

        Dwein

        One of the BEST Purchase Ever! Research paper to patent filing, it all makes it possible! Huge time saver, and amazing for eBooks too! honestly.. I'm actively using 3 other Paid Ais, but I'm blown away by PaperGuide AI's versatility. It significantly reduces the time and effort required to transition from research to patent!
        See all testimonials

        Who Is This For?

        Clinical Investigatorsdesigning new trials and writing study protocols

        Protocol Writerscreating trial documents for regulatory approval

        Regulatory Affairs Specialistspreparing drug applications and supporting documentation

        CRO Teamsdeveloping protocols for pharmaceutical clients

        Medical Writerscreating regulatory documents and clinical study reports

        Biostatisticiansselecting study designs and statistical methods

        Product Features

        Deep Research AI

        Get comprehensive reports on therapeutic areas with detailed analysis of existing trials and gaps.

        Literature Review

        Compare trial designs across studies in organized tables with endpoint and safety data.

        AI Search

        Ask specific trial design questions and get immediate answers with citations about optimal approaches.

        AI Writer with Citations

        Generate protocol sections like background and methodology with automatic references to relevant studies.

        Chat with Papers

        Ask questions directly to published trial protocols to understand specific design and methodology choices.

        Custom Data Extraction

        Create extraction forms for protocol elements like endpoints, populations, or methods for consistent comparison.

        Speed Up Your Research with Accuracy and Ease

        Frequently Asked Questions