This thesis describes chosen heavy metals which are toxic for human body, characteristic symptoms of chosen metal intoxication types and prevention methods, and examples of the influence of lead on central nervous system, on anomalies in fetal nervous system development and tobacco smoke toxins on fetal development during pregnancy.
The use of disposable screen-printed electrodes for stripping analysis is described. The graphite surface of the working electrode can be used as substrate for plating a thin mercury film, which allows the electrochemical preconcentration of heavy metals. Detection limits around ppb level were obtained for different metals (Pb(II), Cd(II), Cu(II)). Moreover chemically modified screen-printed electrodes were developed in order to have mercury-free devices to accumulate heavy metals. Different substances (ion-exchangers and ligands) were tested.