THE STUDY OF GENETICS IN ASTHMATIC CHILDREN
88 Citations•1989•
N. Koya, H. Tako, K. Okumura
Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology
The results suggest no significant difference in the frequency of HLA antigen in the 3 groups.
Abstract
HLA population study was performed in asthmatic children. The frequencies of HLA class I (A, B, C), II (DR, DQ, DRW) antigens were measured in the following groups. Forty-eight asthmatic children, aged 5-17 years, were diagnosed by clinical manifestation alone. Thirty-one asthmatic children, aged 5-16 years, were diagnosed by clinical manifestation and high serum level of DF-specific IgE antibody, Fifty-two healthy control group, aged 15-45 years, were documented by absence of symptoms, negative DF specific IgE antibody and negative DF skin test. Our results suggest no significant difference in the frequency of HLA antigen in the 3 groups.