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Immunology

88 Citations2001
John A. Smith
Current Protocols in Molecular Biology

The transcription factor determines B-cell lineage commitment by actively suppressing alternative lineage choices, so Pax5-deficient pro-B cells can take various differentiation pathways.

Abstract

illustration The transcription factor determines B-cell lineage commitment by actively suppressing alternative lineage choices, so Pax5-deficient pro-B cells can take various differentiation pathways.