A Novel
Dili and AFP had significantly higher %ID/gram than either Tl-201 or Tc-99m sestamibi when considered across all tumor types when considered across all tumor types at both 60 minutes and 24 hours.
Abstract
MCF-7, T47, MTW9A) and estrogen receptor negative (MDA MB-231, BT20) human breast cancer xenografts were grown subcutaneously in the lateral thorax region of immunosuppressed mice (CB-17 SCID). Quantitative comparisons of percent-injected dose per gram of tissue (%ID/gram) and tumor to thigh ratio (T/Th) were performed at 0-60 minutes and at 24 hours following injection. For most tumors, T/Th for AFP and Dili was significantly greater than T/Th for Tc-99m sestamibi and Tl-201. Dili and AFP had significantly higher %ID/gram than either Tl-201 or Tc-99m sestamibi when considered across all tumor types (BT20, MCF7, MDA, MTW9A, T47) at both 60 minutes and 24 hours.