All that are described are novel heterocyclic compounds of general formulae and (values of radicals are given in invention formula), pharmaceutical compositions containing them and application of said heterocyClic compounds for treatment disorders mediated with MAP kinase cascade.
FIELD: medicine. SUBSTANCE: described are novel heterocyclic compounds of general formulae and (values of radicals are given in invention formula), pharmaceutical compositions containing them and application of said heterocyclic compounds for treatment disorders mediated with MAP kinase cascade. EFFECT: increase of compound efficiency. 67 cl, 106 ex, 2 tbl, 2 dwg