Novel heterocyclic compounds
The present invention includes a method which comprises administering an effective amount of a compound (I) for the required certain mammals.
Abstract
The present invention relates to novel heterocyclic compounds of general formula (I), their derivatives, analogs, tautomeric isomers, stereoisomers, polymorphs acids, hydrates acids, solvates include, pharmaceutically acceptable salts and compositions, their metabolites acids and prodrugs. The present invention particularly provides novel heterocyclic compounds of general formula (I). Furthermore, immune diseases in a mammal, inflammatory, pain disorders, rheumatoid arthritis; osteoporosis; multiple myeloma; uveitis; acute and chronic myelogenous leukemia; ischemic heart disease; atherosclerosis; cancer, ischemic-induced cell damage ; pancreatic beta cell destruction; osteoarthritis; rheumatoid spondylitis; gouty arthritis; inflammatory bowel disease; adult respiratory distress syndrome (ARDS); psoriasis; Crohn's disease; allergic rhinitis; ulcerative colitis; anaphylaxis; contact resistance dermatitis; muscular degeneration; cachexia; asthma; bone resorption diseases; ischemic reperfusion injury; brain injury; multiple sclerosis; sepsis; septic shock; toxic shock syndrome; fever, treatment of muscular aches due to infection in the method, it includes a method which comprises administering an effective amount of a compound (I) for the required certain mammals. [Formula 1]