The Role of Genetics
Basic concepts in molecular biology focusing on deoxyribonucleic acid replication and production of proteins are reviewed, including how changes in the genetic sequence, whether through mutations or recombination, may affect patients.
Abstract
Oncology Issues January/February 2011 nderstanding how genetics and molecular techniques relate to the care of oncology patients has become increasingly important over the past decade. A basic understanding of these techniques is now necessary to help care appropriately for these patients. This article will review some basic concepts in molecular biology focusing on deoxyribonucleic acid (DNA) replication and production of proteins. It will also discuss how changes in the genetic sequence, whether through mutations or recombination, may affect patients. Finally we will discuss specific examples with direct correlation to patient care.