The dopamine connection
88 Citations•2004•
M. Horne
journal unavailable
As Parkinson's disease progresses, nerve cells compensate for the death of neurones by increasing the number of connections they make, but Malcolm Horne has found that an accompanying tenfold increase in the production of the neurotransmitter dopamine sends the disease spiralling out of control.
Abstract
As Parkinson's disease progresses, nerve cells compensate for the death of neurones by increasing the number of connections they make. However, Malcolm Horne has found that an accompanying tenfold increase in the production of the neurotransmitter dopamine sends the disease spiralling out of control.