Novel Heterocyclic Compounds
The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
Abstract
A compound of formula (I) in which Z is selected from (a), (b), (c), (d), (e), (f), (g), (h), (i), (j), and (k). The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.