In 6 cases of diabetes 4 showed arterial changes involving the islands, one degeneration of those bodies, and in one there was no diabetes, but the reverse does not hold good.
sclerosis, lipomatosis, or other moderate changes. In more than half there was definite change in the islands. No case of extensive disease of the islands has been reported without diabetes, but the reverse does not hold good. In some cases there may be perverted function of the islands, in others the liver or nervous system may be at fault. Pearce14 states that if one-fourth of the pancreas is left in situ, or is transplanted elsewhere, diabetes does not occur. The form of pancreatitis responsible for diabetes is the chronic interacinous, in which the islands are involved. In 6 cases of diabetes 4 showed arterial changes involving the islands, one degeneration of those bodies, and in one there was no