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Management of Depression in Adults

142 Citations2024
Gregory E. Simon, Nathalie Moise, David C. Mohr

Effective first-line depression treatments include specific forms of psychotherapy and more than 20 antidepressant medications, which have approximately equal likelihood of success based on a network meta-analysis.

Abstract

Effective first-line depression treatments include specific forms of psychotherapy and more than 20 antidepressant medications. Close monitoring significantly improves the likelihood of treatment success.