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A mitochondria-targeted near-infrared fluorescent probe for imaging viscosity in living cells and a diabetic mice model

108 Citations2021
Bochao Chen, Shumei Mao, Yanyan Sun

A mitochondria-targeted near-infrared fluorescent probe NIR-V with 700 nm emission was designed to monitor cell viscosity changes with high selectivity and sensitivity, which was applied to detect the intracellular Viscosity and image pancreatic tissue in a diabetic mouse model.

Abstract

<p>A mitochondria-targeted near-infrared fluorescent probe <bold>NIR-V</bold> with 700 nm emission was designed to monitor cell viscosity changes, which was applied to detect the intracellular viscosity and imagine pancreatic tissue in diabetic mouse model.</p>