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Cardiometabolic multimorbidity, genetic risk, and dementia: a prospective cohort study
127 Citations•2022•
Xin You Tai, Michele Veldsman, Donald M. Lyall
Cardiometabolic multimorbidity was independently associated with the risk of dementia and extensive brain imaging differences to a greater extent than was genetic risk, and targeting cardiometabolism with a low genetic risk might help to reduce therisk of dementia.
Abstract
Wellcome Trust, Alzheimer's Research UK, Alan Turing Institute/Engineering and Physical Sciences Research Council, the National Institute for Health Research Applied Research Collaboration South West Peninsula, National Health and Medical Research Council, JP Moulton Foundation, and National Institute on Aging/National Institutes of Health.