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Mortality in Persons With Autism Spectrum Disorder or Attention-Deficit/Hyperactivity Disorder

116 Citations2022
Ferrán Catalá-López, Brian Hutton, Matthew J. Page

This systematic review and meta-analysis evaluates the risk of both all-cause and cause-specific mortality among persons with autism spectrum disorder or attention-deficit/hyperactivity disorder and their first-degree relatives.

Abstract

This systematic review and meta-analysis found that ASD and ADHD are associated with a significantly increased risk of mortality. Understanding the mechanisms of these associations may lead to targeted strategies to prevent avoidable deaths in high-risk groups. The substantial heterogeneity between studies should be explored further.