Traumatic brain injury accelerates kindling epileptogenesis in rats
27 Citations•2015•
Mansoureh Eslami, Elham Ghanbari, Mohammad Sayyah
Unlike the animal models of PTE in which recurrent seizures occur spontaneously after TBI, in this study, epilepsy is elicited by kindling stimulations.
Abstract
Traumatic brain injury facilitates acquisition of epilepsy in both chemical and electrical kindling models. Combination of trauma and kindling can be considered as an inexpensive and time-saving animal model in PTE studies.