Twelve years of SAMtools and BCFtools
14338 Citations•2021•
Petr Danecek, James Bonfield, Jennifer Liddle
The SAMtools and BCFtools packages represent a unique collection of tools that have been used in numerous other software projects and countless genomic pipelines, free for both non-commercial and commercial use.
Abstract
Both SAMtools and BCFtools are freely available on GitHub under the permissive MIT licence, free for both non-commercial and commercial use. Both packages have been installed >1 million times via Bioconda. The source code and documentation are available from https://www.htslib.org.