Synthesis of heterocyclic compounds through nucleophilic phosphine catalysis
137 Citations•2020•
Yifan Huang, Jianning Liao, Wei Wang
The present report summarizes the construction of four to eight-membered heterocyclic compounds containing nitrogen, oxygen and sulphur atoms through phosphine-catalyzed intramolecular annulations and intermolecular Annulations of electron-deficient alkenes, allenes, alkynes and Morita-Baylis-Hillman carbonates.
Abstract
<p>Nucleophilic phosphine catalysis is a practical and powerful tool for the synthesis of various heterocyclic compounds with the advantages of environmentally friendly, metal-free, and mild reaction conditions.</p>