Home / Papers / Diagnostic strategies for SARS-CoV-2 infection and interpretation of microbiological results
Diagnostic strategies for SARS-CoV-2 infection and interpretation of microbiological results
173 Citations•2020•
Giorgia Caruana, Antony Croxatto, Alix T. Coste
The present review discusses performances, limitations and use of current and future diagnostic tests for SARS-CoV-2 and real-time RT-PCR remains the reference method for diagnosis.
Abstract
Real-time RT-PCR remains the reference method for diagnosis of SARS-CoV-2 infection. On the other hand, notwithstanding its varying sensitivity according to the time of infection, serology represents a valid asset (a) to try to solve possible discrepancies between a highly suggestive clinical and radiological presentation and negative RT-PCR, (b) to solve discrepancies between different PCR assays and (c) for epidemiological purposes.