Trispecific natural killer cell nanoengagers for targeted chemoimmunotherapy
102 Citations•2020•
Kin Man Au, Steven Park, Andrew Z. Wang
A nanoparticle-based trispecific NK cell engager (nano-TriNKE) platform that can target epidermal growth factor receptor-overexpressing tumors and promote the recruitment and activation of NK cells to eradicate these cancer cells is reported.
Abstract
<jats:p>A trispecific natural killer cell engager platform has been successfully engineered for EGFR-targeted chemoimmunotherapy.</jats:p>