Therapeutic options for CTLA-4 insufficiency
113 Citations•2021•
David Egg, Ina Caroline Rump, Noriko Mitsuiki
Systemic immunosuppressants and abatacept may provide partial control but require ongoing administration and allogeneic hematopoietic stem cell transplantation offers a possible cure for patients with CTLA-4 insufficiency.
Abstract
Systemic immunosuppressants and abatacept may provide partial control but require ongoing administration. Allogeneic hematopoietic stem cell transplantation offers a possible cure for patients with CTLA-4 insufficiency.