Oral Relugolix for Androgen-Deprivation Therapy in Advanced Prostate Cancer
403 Citations•2020•
Neal D. Shore, Fred Saad, Michael S. Cookson
In this phase 3 trial involving men with advanced prostate cancer, relugolix achieved rapid, sustained suppression of testosterone levels that was superior to that with leuprolide, with a 54% lower risk of major adverse cardiovascular events.
Abstract
In this trial involving men with advanced prostate cancer, relugolix achieved rapid, sustained suppression of testosterone levels that was superior to that with leuprolide, with a 54% lower risk of major adverse cardiovascular events. (Funded by Myovant Sciences; HERO ClinicalTrials.gov number, NCT03085095.).