Top Research Papers on Biotechnology

The aim of this review is to provide an overview of the current state of Archaea Biotechnology by describing the actual state of research and development as well as the industrial utilization of archaeal cell factories, their role and their potential in the future of sustainable bioprocessing, and to illustrate their physiological and biotechnological potential.

This book is a thoughtful effort in bringing forth bioremediation and restoration of the ecosystems degraded by pesticides and heavy metal pollution. Readers will find in it a comprehensive account of the treatment technologies from turning the unsustainable to sustainable.

Aside from fully discussing processes, Separation Processes in Biotechnology includes sections on concentration separation and operation, purification operations, and product release and recovery.

Biotechnological Applications of Biomass provides a comprehensive overview of the current state of the art of biomass utilization in agriculture and pharmaceuticals. The information contained herein is useful to researchers and other readers interested in biomass utilization and production of bioproducts.

The essence, opportunities, responsibilities, and challenges encountered in marine biotechnology are synthesized and the attainment and valorization of directly derived or bio-inspired products from marine organisms are outlined.

Current Developments in Biotechnology and Bioengineering: Advanced Membrane Separation Processes for Sustainable Water and Wastewater Management - Case Studies and Sustainability Analysis gives an up-to-date review and research developments of MBR systems (including hybrid systems) in wastewater treatment in terms of pollutant removal, nutrient recovery, and energy production as well as the achievement of energy efficiency of the process itself. The current challenges that hinder the application and industrialization of MBR technology as well as knowledge gaps and future research perspectives ...

Abstract This book covers the biotechnology of all the major perennial fruit and nut species, including Actinidia spp., Anacardium occidentale , Mangifera indica , Pistacia vera , Annona spp., Cocos nucifera , Elaeis guineensis , Phoenix dactylifera , Ananas comosus , Carica papaya , Garcinia mangostana , Diospyros kaki , Vaccinium spp., Castanea spp., Carya illinoinensis , Juglans regia , Persea americana , Theobroma cacao , Musa spp., Psidium guajava , Olea europaea , Averrhoa carambola , Passiflora spp., Eriobotrya japonica , Fragaria × ananassa , Malus × domestica , Prunus persica , Prunus...

The bioluminescence reaction is now routinely used for gene assays, the detection of protein-protein interactions, high-throughput screening (HTS) in drug discovery, hygiene control, analysis of pollution in ecosystems and in vivo imaging in small mammals.

Microbial fermentations are used for the sustainable production of a range of products. Due to increasing trends in the food sector toward plant-based foods and meat and dairy product substitutes, microbial fermentation will have an increasing role in this sector, as it will enable a sustainable and scalable production of valuable foods and food ingredients. Microbial fermentation will also be used to advance and expand the production of sustainable chemicals and natural products. Much of this market expansion will come from new start-ups that translate academic research into novel processes a...

This Review presents a comprehensive overview of current development leveraging genomic analyses and revolutionary new plant breeding technologies to enhance food crop traits through agricultural biotechnology.

B. licheniformis is a Gram positive spore-forming bacterial species of high biotechnological interest with numerous present and potential uses, including the production of bioactive compounds that are applied in a wide range of fields.

This Perspective is to highlight a few of mistaken concepts in terahertz research, to distinguish them from the many interesting works that continue to emerge from the fruitful marriage of terahertz with biology and medicine.

Nonlinear nonparametric machine learning techniques are more efficient than classical statistical models in handling large amounts of complex and nondeterministic information with “multiple-independent variables versus multiple-dependent variables” nature.

The role of algae, fungi, bacteria in the biodegradation, and biotechnological methods to enhance degradation are discussed, e.g., gene editing tools and bioinformatics.

The origin of antifreeze proteins is summarized, the diversity of their species-specific properties and functions are described, and the related biotechnology is highlighted on the basis of both laboratory tests and bioinformatics analysis.

This review is focused on the metabolic features of Rhodococcus genus and their potential use in biotechnology strategies for the production of compounds with environmental, industrial, and medical relevance such as biosurfactants, bioflocculants, carotenoids, triacylglycerols, polyhydroxyalkanoate, siderophores, antimicrobials, and metal-based nanostructures.

This review covers the latest advances in computational methods for enzyme engineering and presents many successful case studies, including theoretical approaches that identify hotspots on the protein sequence for mutagenesis and predict suitable alternatives for selected positions with expected outcomes.

This review highlights the influence of “omics” technologies on the production of biofuels and bioproducts by metabolic engineering, and discusses the application of ‘omics’ technologies to agricultural and food biotechnology.

This review will deal with the incidence of technological and biotechnological processes on the elaboration of fruit vinegars other than grapes.

Biotechnology and the Control of Myiasis Diseases, The Major Histocompatibility Complex and Parasite Immunity, and Genetic Markers for the Selection of Parasite Resistance in Livestock are reviewed.

Adopting a more networked approach — linking specialists, infrastructure and ongoing research to de-risk the economic challenges of scale-up and supported by an effective long-term funding strategy — is set to transform the impact of synthetic biology and industrial biotechnology in the bioeconomy.

BIOAVAILABILITY Coal Fly Ash Application to Soils and its Effect on Boron Availability to Plants, T. Matsi and C.D. Tsadilas Bioavailability of Trace Elements in Relation to Root Modification in the Rhizosphere, I.K. Mitsios and N.G. Danalatos Availability of Heavy Metals Applied to Soil through Sewage Sludge, V. Antoniadis, C.D. Tsadilas, V. Samaras, and J. Sgouras Influence of Fly Ash Application on Heavy Metal Forms and Their Availability, C.D. Tsadilas, E. Tsantila, S. Stamatiadis, V. Antoniadis, and V. Samaras Arsenic Concentration and Bioavailability in Soils as a Function of Soil Proper...

Tons of anthropological activities contribute daily to the massive amount of lignocellulosic wastes produced annually. Unfortunately, their full potential usually is underutilized, and most of the biomass ends up in landfills. Lignocellulolytic enzymes are vital and central to developing an economical, environmentally friendly, and sustainable biological method for pre-treatment and degradation of lignocellulosic biomass which can lead to the release of essential end products such as enzymes, organic acids, chemicals, feed, and biofuel. Sustainable degradation of lignocellulosic biomass via hy...

Abstract The National Center for Biotechnology Information (NCBI) provides a large suite of online resources for biological information and data, including the GenBank® nucleic acid sequence database and the PubMed® database of citations and abstracts published in life science journals. The Entrez system provides search and retrieval operations for most of these data from 34 distinct databases. The E-utilities serve as the programming interface for the Entrez system. Custom implementations of the BLAST program provide sequence-based searching of many specialized datasets. New resources release...

Recent advances in the biosynthesis and bioactivities of cannflavins, which are prenylated (C5) and geranylated (C10) flavones that are relatively unique to C. sativa, set the stage for interrogating the health benefits of C.sativa flavonoids, deciphering the contribution of flavonoid to the entourage effect, and developing drugs.

The recent advances and prospects in genetic engineering, systems and synthetic biology, and applications of P. putida as a cell factory are summarized and Pseudomonas putida advances to a global industrial cell factory.

This review focuses on the latest research, mostly aimed at the development of designer exosomes using parental cell-based engineering and their application in cancer treatment and regenerative medicine.

An overview of the contemporary progress in the field of biodegradable polymers, especially polyhydroxy-alkanoates (PHAs), is provided to attract researchers and stakeholders to further exploit these renewable resources to produce biodesgradable plastics on a commercial scale.

The whole lipid biotechnology of thraustochytrids is overviewed to provide the background information for researchers and to improve the efficiency of lipid extraction and the further application of biomass residues.

The most important applications of CRISPR–Cas in increasing plant yield, quality, disease resistance and herbicide resistance, breeding and accelerated domestication, and recent breakthroughs in CRISpr–Cas plant biotechnologies improve reagent delivery, gene regulation, multiplexed gene editing and directed evolution.

Allowing comprehensive exploration of diverse experimental landscapes through high-throughput screening techniques to identify the best performing strain and/or those carrying the desired trait is recommended.

The biotechnological processes for the production of RF and its cognate cofactors are reviewed in this article and it is shown that developing microbial cell factories that are capable of efficiently producing flavin nucleotides at low cost is an increasingly attractive approach.

The existing and emerging production approaches, applications, developments, and global need for enzymes are discussed, with special emphasis given to the predominantly utilized hydrolytic microbial enzymes in industrial bioprocesses.

The most significant factors that can improve HTS efficiency are discussed, including the construction of screening libraries with high diversity and the use of new detection methods to expand the search range and highlight target compounds.

This tutorial review highlights imaging-guided precise SDT, which allows choosing the best treatment option and monitoring the therapy response in real-time, as well as recent clinical trials based on SDT.

This review provides information about the status of the use biotechnology-based techniques for the conservation of endemic plant species, with particular attention given to cryopreservation, since is the only long-term ex situ conservation strategy that can complement and support the other conservation measures.

This review intends to present some of the latest studies on the lipase A from Candida antarctica (CALA), which is among the most stable ones and has some capability to attack the sn-2 position of triglycerides.

The present review highlights the recent advances in the biotechnological production of erythritol and mannitol and summarizes the benefits of using the two polyols in the food and pharmaceutical industries.

It is a feasible strategy to establish a plant to produce β-carotene by using metabolic engineering technology and optimizing the fermentation of engineered strains, which has the advantages of low environmental pollution, low production costs and a high yield in addition to broad development prospects.

New insights are provided regarding the potential of microalgae replacing soy protein, fish oil, and palm oil and being used as cell factories in modern industrial biotechnology to produce designer feed, recombinant proteins, biopharmaceuticals, and vaccines.