Top Research Papers on Biotechnology

Stabilization and reusability of enzyme transglutaminase (TGM) are important goals for the enzymatic process since immobilizing TGM plays an important role in different technologies and industries. TGM can be used in many applications. In the food industry, it plays a role as a protein-modifying enzyme, while, in biotechnology and pharmaceutical applications, it is used in mediated bioconjugation due to its extraordinary crosslinking ability. TGMs (EC 2.3.2.13) are enzymes that catalyze the formation of a covalent bond between a free amino group of protein-bound or peptide-bound lysine, which ...

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This review will provide updates on the landscape of phage applications for the biocontrol of pathogens in industrial settings and healthcare, and the advantages of using bacteriophages appear as a viable and promising alternative.

This study has developed and optimised a new faster version of the HaloPlex Target enrichment technique that allows the implementation of molecular barcodes used to increase the sensitivity for rare alleles and reduce errors in sequencing data.

Overall, environmental biotechnology needs at least three steps to prove its effectiveness from concept testing in laboratory, establishment of the mechanisms involved, workability in complex system and ecosystems, and lastly the implementation and practice on site.

This review aims to provide an overview of this emerging field of quantum biotechnology, introducing current capabilities, future prospects, and potential areas of impact and focuses on the four key areas of quantum‐enabled sensing, quantum‐ enabled imaging, quantum biomolecular control, and quantum effects in biology.

The essence, opportunities, responsibilities, and challenges encountered in marine biotechnology are synthesized and the attainment and valorization of directly derived or bio-inspired products from marine organisms are outlined.

The ecological role of Chloroflexota in such environments with the potential application of their metabolisms in biotechnological approaches is correlated with the potential application of their metabolisms in biotechnological approaches.

An overview of holographic biosensing in applications such as pH, alcohol, ion, glucose, and drug detection, alongside antibiotic monitoring is provided.

The field of aquaculture has been revolutionized by the introduction of biotechnology and with the help of advanced genetic research, scientists have been able to enhance the growth of fish production.

The biotechnological production of butanol and other accompanying solvents has a history of more than a century and currently represents an alternative to produce desirable chemicals from various waste streams, in accordance with the concept of the circular economy. This review article summarizes the current state of potential industrial production, introduces the main solvent producers, solventogenic clostridia and their metabolism, together with the main aspects that influence physiological and production characteristics. The last part is devoted to substrates that can be used for biobutanol...

The main objective of this review is to delineate and discuss the critical factors involved in the liquid target production of radiometals, including type of salt solution, solution composition, beam energy, beam current, the effect of irradiation duration and challenges posed by in-target chemistry in relation with irradiation parameters.

Emerging applications of microfluidic technologies on microalgal processes in cell sorting, cultivation, harvesting, and applications in biofuels, biosensing, drug delivery, and nutrition are reviewed.

B. licheniformis is a Gram positive spore-forming bacterial species of high biotechnological interest with numerous present and potential uses, including the production of bioactive compounds that are applied in a wide range of fields.

The bioluminescence reaction is now routinely used for gene assays, the detection of protein-protein interactions, high-throughput screening (HTS) in drug discovery, hygiene control, analysis of pollution in ecosystems and in vivo imaging in small mammals.

This chapter discusses kinship, adoption and adoption and Assisted Reproductive Technologies in Lithuania, as well as an Examination of Norwegian Legislation, which highlighted the importance of adoption in the context of lesbian, gay, bisexual and transgender (LGBT) lives.

The anti-inflammatory and antioxidative effects of NZD are illustrated.

The demand for fossil fuels for industry, agriculture, transportation, and private sectors is sharply increasing globally [...].

A perspective on the recent developments in biotechnology and molecular biology is provided to establish the potential of these technologies for the genetic improvement of grapevine.

The aim of this study was to analyze the number of Adverse Drug Reactions published as case reports (PubMed indexed journals) from January 2018 to June 2019, and observe if they are translated in regulatory frameworks like Vigibase, and package inserts.

The National Center for Biotechnology Information (NCBI) produces a variety of online information resources for biology, including the GenBank® nucleic acid sequence database and the PubMed® database of citations and abstracts published in life science journals. NCBI provides search and retrieval operations for most of these data from 35 distinct databases. The E-utilities serve as the programming interface for the most of these databases. Resources receiving significant updates in the past year include PubMed, PMC, Bookshelf, RefSeq, SRA, Virus, dbSNP, dbVar, ClinicalTrials.gov, MMDB, iCn3D a...

Past breakthroughs in fungalBiotechnology are highlighted, requirements to advance fungal biotechnology even further are discussed, and on the horizon of new breakthroughs with the highest potential to positively impact both research and society are touched.

The versatile potential applications of cyanobacteria in biotechnology could be their significant growth rate and survival in severe environmental conditions due to their distinct and unique metabolic pathways as well as active defensive mechanisms.

The research aims at evaluating the effectiveness and accuracy of different convolutional neural networks models in the automatic diagnosis of COVID-19 from X-ray images as compared to diagnosis performed by experts in the medical community.

This Perspective is to highlight a few of mistaken concepts in terahertz research, to distinguish them from the many interesting works that continue to emerge from the fruitful marriage of terahertz with biology and medicine.

A multidisciplinary scientific perspective is proposed that leads to a holistic understanding of conifers from the perspective of the latest technical, computer, and scientific advances and highlights the deep connection that all scientific contributions to conifer can have in each other as fully interrelated communicating vessels.

The development of plant-based biomanufacturing could offer a more sustainable and cost-effective method to produce useful products compared to traditional manufacturing process.

Two efficient, scalable routes to bis-1,2,4-oxadiazole have been developed by tandem Staudinger/aza-Wittig reaction from the same starting material diaziglyoxime, isocyanates and triphenylphosphonium in good yields, providing proficient methods of making nitrogen-containing heterocyclic rings.

This review summarizes the latest and most comprehensive information regarding the absorption, distribution, metabolism, and excretion of the Scutellaria baicalensis components in vivo and examined the main advantages of nanodrug delivery systems.

Extracellular Vesicle (EV)-based therapy has been identified as a leading alternative approach in several disease models and has been documented for its strong neuro-regenerative capacity.

The correlation analysis indicated that EI was significantly negatively related to MMSE scores of MCI patients (r = -0.131), and the area under the curve was 0.704±0.045 for NC-MCI in 70-75 years old groups.

To gain a basic understanding of the biology of the plant, this review has discussed how biotechnological tools, such as cell and tissue culture, micropropagation, and molecular marker technology, have been used to enhance pitaya germplasm.

Agricultural biotechnology is becoming the major sector in crop improvement through the use of scientific techniques for the modification of genes conferring resistance to biotic, abiotic stress and improving the quality of crops. With the evolvement from Mendelian genetics to molecular biotechnology, there have been several developments in the field of crop improvement. Recent biotechnological advances have aimed towards removing the physiological constraints of the crops and increasing crop yield potential. With the use of different tools of agricultural biotechnologies like genetic engineer...

Sustainable agriculture is an approach that prioritizes meeting current food and fiber production needs while conserving and enhancing natural resources for future generations while striking a balance between economic viability, environmental stewardship, and social responsibility.

The current challenge of research is to select from the wide variety of characterized microorganisms and compounds, those which could provide rapid answers to crucial questions about human or animal health or more generally relating to society’s demands for medicine, pharmacology, nutrition or everyday well-being.

Part 1 Technological innovations: capillary electrophoresis/mass spectrometry for the determination of bioactive proteins and peptides and application of HPCE analysis to process monitoring in biotechnology.

Through a detailed examination of both the biosynthesis and biotechnological advances in HT production, this review contributes valuable insights to the field, charting a course towards the sustainable and scalable production of this multifaceted compound.

This paper presents a meta-analyses of the determinants of apoptosis, a type of cell death that is known as “cell reprograming” and which has been associated with Parkinson’s disease.

It is become apparent that more and more AI‐based tools are being developed and used for biocatalysis and biotechnology, and biotechnology, as a rapidly growing interdisciplinary field, stands to benefit greatly from these developments.

This study utilizes bibliometric analysis to explore the landscape of biotechnology research from a comprehensive perspective, focusing on thematic clusters, research trends, research opportunities, and author collaboration networks, offering valuable insights for future research directions and strategic industry applications.

How the efficient central metabolism of methanoarchaea could be harnessed for future biotechnology applications is discussed.

Spondylodiscitis is an infectious process that requires numerous health care professionals to be clearly diagnosed and eventually successfully treated. It implies a variety of microbiological agents and conditions; during the diagnostic workup, it is difficult to correctly identify them, and the clinician has to rapidly choose the correct treatment to avoid permanent injuries to the patient. In this context, we conducted a review to better understand the most suitable use of Positron Emission Tomography with 18-Fluoro-deossi-glucose (FDG PET) in a patient suspected of spondylodiscitis, based o...

SBEPC can enhance drugs' ability to enter the brain and improve the bioavailability of drugs in brain, and can effectively exert the neuroprotective effect on cerebral ischemia-reperfusion injury as compared with SBE.

The functional versatility of Pseudomonas is summarized with particular reference to its peculiarities along with the ecological and biotechnological applications.

The possibility to use transcriptomics, genomics, interspecific hybridization, tissue cultures and plant regeneration, molecular markers, genetic transformation, and genome editing to aid in both the breeding of buckwheat and in the identification and production of metabolites important for preserving human health are reviewed.

To determine tumor volume changes in terms of radiological response in patients with meningioma treated with Gamma Knife Radiosurgery and to analyze the relationship between Total Tumor Volume and Diffusion Tensor Imaging parameters, it is investigated whether the response to treatment can be predicted by pre-radiosur surgery DTI findings.

This review will deal with the incidence of technological and biotechnological processes on the elaboration of fruit vinegars other than grapes.

This review firstly summarizes the biodiversity of sources and the fermentation process of nattokinase, and systematically elucidates the structure, catalytic mechanism and enzymatic properties of n attokinase.

The caspase‐3's structure, functions, therapeutic applications, as well as its molecular cloning, protein engineering, and relevant delivery systems are discussed.

Strains of this species produce a plethora of biotechnologically important enzymes, including cellulases, β-glucanases, xylanases, lipases, proteases, and α-amylases, which demonstrate the importance of G. candidum for agrifood- and bio-industries.